姓名:尹晓敏
职称:副教授
个人简介:江苏南通人,医学博士。
专业研究领域:神经退行性疾病的机制研究。
专著与论集:
1. yin x, li y, fan x, huang f, qiu y, zhao c, zhou z, gu q, xia l, bao j, wang x, liu f, qian w. sirt1 deficiency increases o-glcnacylation of tau, mediating synaptic tauopathy. mol psychiatry. 2022;27(10):4323-4334.
2. yin x, zhao c, qiu y, zhou z, bao j, qian w. dendritic/post-synaptic tau and early pathology of alzheimer's disease. front mol neurosci. 2021;14:671779.
3. yin x, zhou z, qiu y, et al. sirt1 regulates tau expression and tau synaptic pathology. j alzheimers dis. 2021;84(2):895-904.
4. yin x, jiang x, wang j, et al. sirt1 deacetylates sc35 and suppresses its function in tau exon 10 inclusion. j alzheimers dis. 2018;61(2):561-570.
5. yin x, jin n, shi j, et al. dyrk1a overexpression leads to increase of 3r-tau expression and cognitive deficits in ts65dn down syndrome mice. sci rep. 2017;7(1):619.
6. yin x, jin n, gu j, et al. dual-specificity tyrosine phosphorylation-regulated kinase 1a (dyrk1a) modulates serine/arginine-rich protein 55 (srp55)-promoted tau exon 10 inclusion. j biol chem. 2012;287(36):30497-30506.
主要科研项目
主持国家自然科学基金项目1项,江苏省高校自然科学基金1项。
讲授课程
生物化学与分子生物学
指导研究生情况